PDRN skin treatment
Polynucleotide (PDRN) injections that support tissue repair and collagen renewal, popular for their healing and skin-quality effect rather than added volume.
How it works
PDRN is a purified DNA-derived molecule that signals the skin to repair and regenerate itself, improving elasticity, hydration and overall skin quality without adding bulk the way a filler does.
Areas we treat
Full face, under-eyes and neck; also used for scar and post-procedure skin recovery.
The session and aftercare
20-30 minutes, mild redness or small bumps that settle within a day or two. A course of 3 sessions, 2-3 weeks apart, is typical.
Who it suits
- Wanting skin-quality improvement without volume
- Under-eye dullness or crepiness
- A regenerative option alongside injectables
A newer generation of skin booster
PDRN, or polydeoxyribonucleotide, is derived from purified salmon DNA fragments and works by activating adenosine A2A receptors in the skin, which promotes tissue repair, boosts local blood flow and encourages collagen synthesis. It is increasingly used both as a stand-alone skin-quality booster for dull, stressed or post-procedure skin and as a healing accelerant after laser or microneedling sessions, with a typical course of 3-4 sessions spaced two to three weeks apart.
Not sure if PDRN is right for you?
Send a few details and Dr. Alaa will get back to you personally on WhatsApp or email, no obligation.
This page is for education and is not a substitute for personal medical advice. Suitability, risks and results are assessed at consultation.
Related treatments
Frequently asked questions
What is PDRN?
PDRN (polynucleotide) is a purified DNA-derived molecule, originally used in wound healing, that signals skin cells to repair and regenerate. Injected into the skin it improves hydration, elasticity and overall quality without adding volume.
How much does PDRN cost in the Maldives?
Pricing depends on the area treated and how many sessions your skin needs. After a short consultation (in person or over WhatsApp with photos) we share an exact, no-obligation quote.
How many PDRN sessions will I need?
A course of 3 sessions, spaced 2-3 weeks apart, is typical for a first course, with occasional top-ups after that depending on how your skin responds.
Does PDRN hurt?
Most people feel a series of small pinpricks. Any discomfort is brief and settles quickly; numbing cream can be used for anyone needle-anxious.
When will I see results from PDRN?
Skin quality, hydration and glow improve gradually over the course of treatment, with most people noticing a difference by the second or third session rather than overnight.
What are the risks and side effects of PDRN?
PDRN has a strong safety profile. The most common effects are mild redness, small bumps or slight bruising at injection points, which usually settle within a day or two.
How is PDRN different from a filler or Profhilo?
A filler adds volume and shape. PDRN and Profhilo both work on skin quality rather than volume, PDRN through tissue repair signalling, Profhilo through deep, sustained hydration; which suits you best is assessed at consultation.
Can PDRN be combined with other treatments?
Yes. It is often paired with skin boosters, microneedling or scar treatments as part of a broader regenerative plan, sequenced to avoid overlapping downtime.
